HONG KONG (AP) — Global shares were mostly lower Friday as investors mulled uncertainties brought by U.S. President Donald Trump’s latest tariffs.

The future for the S&P 500 lost 0.4% and that for the Dow Jones Industrial Average retreated 0.2%.

In Europe, Germany’s DAX declined 0.6% to 22,537.65 and the CAC 40 in France slid 0.5% to 7,950.56.

Britain’s FTSE 100 gained 0.2% to 8,680.66 after retail sales , with a smaller-than-expected trade deficit in February.

Thailand’s SET lost 1.1% after a powerful earthquake centered in Myanmar rattled the region, causing the prime minister to declare a state of emergency for the capital, Bangkok.

Tokyo’s benchmark Nikkei 225 sank 1.8% to 37,120.33 on renewed heavy selling of auto-related shares following Trump’s announcement he plans to impose 25% tariffs on auto imports.

Toyota Motor Corp. shares lost 2.8% while Honda Motor Co. dipped 2.4%.

A report that Tokyo’s inflation rate rose to 2.9% this month spurred expectations that the Bank of Japan will likely raise its key interest rate at its May policy board meeting.

In South Korea, the Kospi sank 1.9% to 2,557.98. Hyundai Motor Co. lost 3.5% and Kia Corp.’s shares lost 2.7%.

Hong Kong’s Hang Seng turned lower, falling 0.7% to 23,426.60. The Shanghai Composite index lost 0.7% to 3,351.31.

Australia’s S&P/ASX200 edged 0.2% higher, closing at 7,982.00. Taiwan’s Taiex tumbled 1.6%.

On Thursday, Wall Street ended with modest losses as Trump’s tariff escalation created winners and losers among auto stocks. Better-than-expected data on the economy also helped support the market.

The S&P 500 slipped 0.3% to 5,693.31 and the Dow Jones Industrial Average fell 0.4% to 42,299.70. The Nasdaq composite fell 0.5% to 17,804.03.

General Motors sank 7.4%, one of the market’s sharper losses. Ford Motor dropped 3.9%.

Even U.S. automakers selling vehicles in the country can feel the pain of such tariffs because their supply chains are spread throughout North America and beyond. Trump says he wants more manufacturing to take place within the United States.

Among the uncertainties are how the U.S. government will determine how to apply tariffs to parts that are compliant with the free-trade agreement that the United States and Mexico and Canada have, but are not made entirely within the United States. Tracking parts could be difficult.

Stock markets worldwide will likely remain shaky as an April 2 deadline approaches for more tariffs. That’s what Trump has called “Liberation Day,” when he will roll out tariffs tailored to the United States’ trading partners. In each case, he said the “reciprocal” tariff will match the burden the other country places on the United States, including things like value-added taxes.